rejuran questions answered by Dr Calvin Chan

10 Questions Everyone Asks About Rejuran

What is Rejuran? Is it really made from salmon sperm? Is Rejuran the same as a dermal filler? Does it hurt to have Rejuran injections? What are the effects of Rejuran and how long does it take for me to see results? Dr Chan answers these often-Googled questions and more.

Dr Calvin Chan Rejuran Blog

1. What is Rejuran?
Rejuran is an injectable skin treatment that’s also commonly referred to as Rejuran Healer, PDRN Therapy, Miracle Healer Injection, or 婴儿针. The treatment was first popularised in Asian countries such as Korea and Japan as it offered a way to achieve soft, smooth, luminous and supple complexion.

Rejuran Healer is an injectable treatment made of polynucleotides (PN), or polydeoxyribonucleotide (PDRN) and these molecules form long chains that are also known as DNA. Simply put, polynucleotide is DNA and the source of this DNA extract is obtained from salmon. Salmon DNA offers multiple benefits for the skin with research indicating that it can address ageing skin concerns by rejuvenating and repairing the skin from inside.

2. Is Rejuran really made from salmon sperm? Does it smell fishy?
Yes, Rejuran is derived from salmon sperm, and no, the injectable product does not smell fishy at all as it has been purified and processed for medical aesthetics use. It is safe, stable and biocompatible with human skin.

The ingredient is said to help with cell repair and regeneration as it has potent regenerative qualities, encouraging cell turnover, helping firm skin and maintain its elasticity, and also offers anti-inflammatory benefits that aid in wound and tissue repair. So, in short, anyone looking to slow down the signs of skin ageing can consider Rejuran Healer.

Rejuran healer with Dr Calvin Chan

3. Is Rejuran safe if I have skin allergies? What are the contraindications?
As it is made from salmon, those who are allergic to salmon should not try the treatment. Other contraindications include patients who are on blood thinners such as warfarin. As Rejuran is an injected treatment, blood thinners would make patient’s skin more prone to bleeding and bruising as a result of the injections.

4. Is Rejuran the same as a dermal filler?
Rejuran is not a dermal filler. It is an injectable substance that has advanced skin reparative factors that can treat skin damage. This covers external skin damage like UV and pollution, as well as internal skin damage from the effects of oxidative stress.

5. Does it hurt to have Rejuran injections? What pain relief options are there?
Rejuran is administered via superficial intradermal injections with a tiny needle, we use extra small 34 gauge needles to minimise pain. To comprehensively treat the entire face, the administration of two to three hundred injections covering the forehead, cheeks, temples, upper and lower eyelids and nasolabial region is recommended.

To combat any discomfort from Rejuran injections, patients can choose to take oral painkillers like paracetamol prior to treatment, and in addition, numbing cream may be introduced. We also have the Zimmer Cryo Cooler, which is a device that cools the epidermis before, during and after an injection is administered to minimise pain and it can also help to decrease instances of swelling. The Zimmer Cryo Cooler is a better option than using ice packs for the same purpose as the latter may not be sterile.

Rejuran treatment for glass skin effect

6. Is there any downtime from Rejuran treatment?
The post-treatment appearance from Rejuran is quite peculiar because it is injected into the skin in multiple dots resulting in tiny raised welts at the site of each injection. Post treatment, it looks like rows of tiny mosquito bites all over the skin. These can take 12-24 hours to fully disappear.

7. What are the benefits of Rejuran and how long does it take to see results?
Despite the drawbacks, Rejuran is gaining popularity as it offers apparent results with visible improvements from one to two weeks after the procedure. Skin problems like erythema or redness usually resolve after two weeks and patients will also see improvement in skin elasticity and observe tighter, lifted skin as the result of collagen synthesis. Other notable effects are balanced sebum and hydration levels, reduced appearances of scars and open pores, and a reduction of hyperpigmentation.

8. How fast is the procedure? What should I do for aftercare?
The procedure itself takes about 15-20 min, excluding the consultation and numbing.
You can expect some swelling (abovementioned welts) immediately after treatment, which usually resolves in a day or two. Avoid excessive heat, sports and exercise a day after the treatment.

Dr Calvin Chan shares on Rejuran benefits

9. What is the recommended treatment protocol for Rejuran?
A course of Rejuran involves three initial treatments about 3 weeks apart, followed by one every six months as maintenance. Results can be seen approximately two to four weeks after the first treatment, as the skin requires time to heal and regenerate.

10. How much does it cost to get Rejuran treatment?
Rejuran costs $800 per 2ml syringe and usually 1 to 3 syringes of Rejuran are needed for the face and neck.

*The information provided in this blog post is not intended as medical advice or instruction on the use of Rejuran. Patients should always consult a medical professional prior to making any decisions or undertaking any actions related to health care.

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